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這是描述信息

GZMK

<p>Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)</p>

Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using GZMK mAb against human GZMK (AA: 27-264) recombinant protein. (Expected MW is 28.7kDa)
Western Blot
Figure 3:Western blot analysis using GZMK mAb against HEK293-6e (1) and GZMK (AA: 27-264)-hIgGFc transfected HEK293-6e (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of Jurkat cells using GZMK mouse mAb (green) and negative control (red).
Flow cytometric
Figure 5:Flow cytometric analysis of MOLT4 cells using GZMK mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 6:Immunohistochemical analysis of paraffin-embedded tonsil tissues using GZMK mouse mAb with DAB staining.

GZMK

貨號 : 32147

規格/濃度 : 1.0mg/ml

價格：

￥ 2557.5

瀏覽量:

1

說明書:

產品規范

Entrez GeneID	3003
別名	TRYP2
克隆編號	5B4A5
分子量	29kDa
同種型	Mouse IgG2b
存放說明	4℃; -20℃ for long term storage
種屬反應性	Human;
免疫原	Purified recombinant fragment of human GZMK (AA: 27-264) expressed in E. Coli.
存儲溶液	Purified antibody in PBS with 0.05% sodium azide

經測試應用

WB	1/500 - 1/2000
IHC	1/200 - 1/1000
FCM	1/200 - 1/400
ELISA	1/10000

描述

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

文獻

1,Brain. 2019 Nov 1;142(11):3411-3427.
2,J Invest Dermatol. 2019 Apr;139(4):930-939.

序列

27-264

圖表

Elisa

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Figure 2:Western blot analysis using GZMK mAb against human GZMK (AA: 27-264) recombinant protein. (Expected MW is 28.7kDa)

Western Blot

Figure 3:Western blot analysis using GZMK mAb against HEK293-6e (1) and GZMK (AA: 27-264)-hIgGFc transfected HEK293-6e (2) cell lysate.

Flow cytometric

Figure 4:Flow cytometric analysis of Jurkat cells using GZMK mouse mAb (green) and negative control (red).

Flow cytometric

Figure 5:Flow cytometric analysis of MOLT4 cells using GZMK mouse mAb (green) and negative control (red).

Immunohistochemical analysis

Figure 6:Immunohistochemical analysis of paraffin-embedded tonsil tissues using GZMK mouse mAb with DAB staining.

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